Abstract:A totally implantable, one‐piece. electromechanical total artificial heart (TAH) intended for permanent human use has been developed. It consists of left and right pusher‐plate pumps (63 cc design stroke volume) sandwiching a thin center piece with a compact electromechanical actuator. The pusher‐plates are shaped conically to accommodate an actuator in the space between them. The actuator consists of an efficient and durable planetary roller screw and direct current brushless motor. The left master alternate pumping mode was implemented utilizing the left pump pusher‐plate position signal. The blood‐contacting surface was coated with a dry gelatin to yield long‐term clot‐free performance. Trileaflet tissue valves of 27 and 23 rnm are used in the inflow and outflow ports. The diameter and thickness of the TAH are 97 and 82 mm, the overall volume is 510 cc, and the weight is 620 g. Anatomic fit was confirmed in 26 heart transplant recipients (body weight 78 kg and surface area 2 m?) without compressing adjacent organs. The pump performance study revealed that the TAH can yield outputs of 3–8 L/ min against the 100 mm Hg afterload with 1–10 mm Hg filling pressure. The input power to the motor ranged From 7 to 12 W, with an efficiency of 18 to 14. A one‐week in vivo calf study demonstrated adequate performance of the TAH, particularly the regulation of atrial pressures. Good anatomic fit and good biocompatibility wer
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机译：摘要：一种完全可植入的一体式产品。已经开发出用于永久人类使用的机电全人工心脏 （TAH）。它由左右推板泵（63 cc 设计冲程容积）组成，夹在带有紧凑型机电执行器的薄中心件上。推板呈圆锥形，以容纳它们之间的空间中的执行器。执行器由高效耐用的行星滚柱丝杠和直流无刷电机组成。利用左泵推板位置信号实现左主交替泵送模式。血液接触表面涂有干明胶，以产生长期无凝块性能。27 和 23 rnm 的三叶组织阀用于流入和流出口。TAH的直径和厚度分别为97和82毫米，总体积为510毫升，重量为620克。在26名心脏移植受者（体重78公斤，表面积2米？）中证实了解剖学上的契合，而没有压迫邻近器官。泵性能研究表明，在 1-10 mm Hg 的填充压力下，TAH 可以产生 3-8 L/min 的输出，而 100 mm Hg 的后负荷。电机的输入功率范围为 7 至 12 W，效率为 18% 至 14%。一项为期一周的犊牛体内研究证明了 TAH 的良好性能，尤其是心房压力的调节。良好的解剖学贴合度和良好的生物相容性
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