Exploratory studies towards AB-ring system of taxanes via intramolecular alkylation reaction. Formation of bicyclo[2.2.2]octanones in preference to bicyclo[5.3.1]undecanes

摘要

An intramolecular alkylation based approach has been explored for the enantiospecific construction of AB-ring system of taxanes starting from 3-allyl-4,4-dimethylcarvone, which however led only to bicyclo[2.2.2]octanones.