To determine the success rate and the safety of percutaneous transluminal coronary angioplasty in smokers (group I) versus nonsmokers (group II), we studied 298 consecutive patients who underwent coronary angioplasty of 371 consecutive lesions. Of these patients, 164 (55percnt;) were smokers and had angioplasty of 210 lesions (57percnt;). The smokers were younger (P0.0001) and predominantly males (P0.01). In smokers, more long lesions and total occlusions were detected (P0.01, and P0.02, respectively). More coronary dissections (without obstructions) occurred in smokers during the angioplasty (P0.006). However, there was no difference between the groups in regard to major complications. The success rate was high and similar in both groups (94percnt; and 93percnt;, respectively). Thus, although there are typical characteristics of smokers and their lesions and a tendency to coronary dissection during angioplasty, percutaneous transluminal coronary angioplasty is as safe and successful in patients who smoke as in patients who do not smoke.
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