Stereochemie planar-chiraler Verbindungen, 3. Mitt.

摘要

1.6-Methano10anulene-2-carboxylic acid (6) was resolvedviaits salts with (+)-and (−)-α-phenethylamine, resp. Two crystallisations from ethanol gave optically pure6(αD20= 250°) as has been shown by application of theNMR-method to the mixture of the diastereomeric phenethylamides of6. Starting from (+)-6several optically active methano10anulenes were prepared and theirCD-spectra recorded. Amongst these are the 2-acetyl, formyl and methyl derivatives and theendo-carbinol14aaccessible from the acetyl compoundviathe cyclic keto