AbstractA retrospective survey on clinical hepatitis in patients with bleeding disorders was performed. Nine episodes of hepatitis non‐A, non‐B occurred in 8 out of 20 patients (40) with mild hemophilia A or von Willebrand's disease, who had been treated with commercial factor VIII concentrates. Only two episodes of hepatitis B occurred during the study period. The non‐A, non‐B attack rate after the first treatment was 40 with factor VIII concentrate obtained from large plasma pools (=2,000 donors) including professional plasma donors as compared to 8 after treatment with factor VIII concentrate obtained from smaller (100–250 donors) plasma pools from Scandinavi
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