A heterotopic liver experiment was set up in which a force field was applied to the transplanted liver. By whatever technique the field was applied it modified the rejection of the liver in a fashion predicted by measurement and an outline of the equipotential lines of force generated by the applied electric field. The findings indicate that rejection is modified by applied force fields. Rejection is undoubtedly, therefore, a surface recognition phenomenon. Cell surfaces bear both recognition and rejection propensities. These can be modified by an externally applied electrochemical charge. Surface recognition phenomenon and surfaces of organs perfused by blood from either a homo or hetero species or an animal of a different species appear to obey electrochemical laws in terms of recognition and electron exchange. A series of attempts to modify rejection in vivo would now seem to be appropriate in experimental animals.
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