首页>
外文期刊>vox sanguinis
>Removal of Parvovirus and Hepatitis A Virus by Metal Chelate Affinity Chromatography during the Preparation of Replenine ®: A High‐Purity Factor IX Concentrate
【24h】
Removal of Parvovirus and Hepatitis A Virus by Metal Chelate Affinity Chromatography during the Preparation of Replenine ®: A High‐Purity Factor IX Concentrate
展开▼
机译:Removal of Parvovirus and Hepatitis A Virus by Metal Chelate Affinity Chromatography during the Preparation of Replenine ®: A High‐Purity Factor IX Concentrate
AbstractThe widespread use of specific virus inactivation techniques such as solvent/detergent, pasteurisation and severe dry‐heat treatment, has greatly increased the safety of coagulation factor concentrates 1. All these techniques are highly effective against known blood‐borne enveloped viruses such as hepatitis B, hepatitis C and HIV. In addition, they should also prove effective against the recently described GB group of hepatitis viruses 3, given that these are enveloped viruses related to hepatiti
展开▼