Development of Functional Requirements for Ex Vivo Pathology Applications of In Vivo Microscopy Systems A Proposal From the In Vivo Microscopy Committee of the College of American Pathologists

摘要

Context.-In vivo microscopy (IVM) allows direct, real-time visualization of tissue histology in living patients without the need for tissue removal, processing, or staining. The IVM technologies in clinical use include confocal microscopy and optical coherence tomography. These technologies also show promise for use with pathology specimens (ex vivo microscopy EVM). However, few systems designed for EVM are commercially available, at least in part because of the lack of defined minimal functional requirements (FRs).