OBJECTIVE: To investigate whether MS is associated with erectile dysfunction (ED) among obese non diabetic individuals. METHODS: A cross-sectional study was carried out to examine the association between the cluster of abnormalities related to the MS and ED as evaluated by the International Index of Erectile Function (IIEF). Fifty consecutive obese i.e. body mass index (BMI) > or =30 kg/m2, nondiabetic whites (age 42.1+/-11.3 yr, BMI 43.3+/-8.7 kg/m2) were recruited. RESULTS: The prevalence of MS as well as that of any MS component were not different between subjects with or without ED. Neither the prevalence of ED (34.3 vs 33.4, p=0.6), nor IIEF score (21.5+/-3.9 vs 21.7+/-3.7, p=0.8), were different between patients with or without MS. IIEF was similar across subgroups of individuals stratified according to the number of MS components and was not related to HOMAIR index. Hypogonadism was observed in 30.8 and 28.1 individuals with and without MS (p=0.58). Testosterone and BMI levels were inversely related (r=-0.3, p=0.04). CONCLUSION: Among obese non-diabetic individuals the risk of developing ED is independent of the presence of MS factors. Testosterone levels progressively decrease with increasing body weight.
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机译：目的：探讨多发性硬化症是否与肥胖非糖尿病患者的勃起功能障碍（ED）有关。方法： 进行一项横断面研究，以检查国际勃起功能指数 （IIEF） 评估的与 MS 和 ED 相关的异常集群之间的关联。招募了 50 名连续肥胖 [即体重指数 （BMI） > 或 =30 kg/m2]、非糖尿病白人（年龄 42.1+/-11.3 岁，BMI 43.3+/-8.7 kg/m2）。结果：MS 的患病率以及任何 MS 成分的患病率在有或没有 ED 的受试者之间没有差异。ED患病率（34.3% vs 33.4%，p=0.6）和IIEF评分（21.5+/-3.9 vs 21.7+/-3.7，p=0.8）在有或没有MS的患者之间没有差异。在30.8%和28.1%的MS患者和不患者中观察到性腺功能减退（p = 0.58）。睾酮和BMI水平呈负相关（r=-0.3，p=0.04）。结论：在肥胖的非糖尿病患者中，发生ED的风险与MS因素的存在无关。睾酮水平随着体重的增加而逐渐降低。
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