Abstract.A reverse passive hemagglutination (RPHA‐G) technique for the automated screening of hepatitis B surface antigen (HBsAg) on the Groupamatic 360 (Kontron International, Zürich, Switzerland) has been developed. It is more sensitive than manual RPHA (RPHA‐M) and nearly as sensitive as radioimmunoassay (RIA); it detects 6 ng/ml of HBsAg, compared to 3 ng/ml by RIA and 25 ng/ml by RPHA‐M. Although it is slightly inferior to the other two methods in respect of specificity, the incidence of false‐positive reactions was only 0.34. The test can also be performed manually without the Gro
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