The state of Oaxaca is one of the most geologically complex and diverse in Mexico. It comprises five tectonos-tratigraphic terranes of contrasting nature that form a sort of tectonic collage where several magmatic pulses were developed. The different lithological assemblages of Oaxaca favored the generation of a variety of ore deposit types, some of which have been a prime source of several commodities for centuries. This paper addresses the time-space relationship between ore deposits and tectono-magmatic events, based upon the available de-scriptions and radiometric ages. Most Meso-to Neoproterozoic ore deposits of Mexico occur in this region, and were formed during the regional granulite-facies metamorphic stage(s) recorded in the Oaxacan Complex. Such deposits are rare element-bearing pegmatites, nelsonites (ilmenite-apatite rich rocks), Ti-rich anorthosites, and pegmatites. The Oaxacan Complex also hosts a number of orogenic gold lodes that were likely formed in more than a single metamorphic episode and still require additional research to clarify their age and geological affiliation. The onset of arc-related magmatism in the Late Carboniferous-Permian is recorded by the intrusion of the calc-alkaline Zaniza, Cuanana and Honduras batholiths, along with several minor deformed and undeformed bodies enclosed in the Oaxacan Complex. Little is known about the metallogeny associated with such magmatism. Although supra-subduction magmatism re-initiated in the Jurassic and is probably responsible for the San Juan Mazatl acute;an Cu porphyry, most of the metallogeny of Oaxaca is tightly linked to the Sierra Madre del Sur (SMS) igneous province, which began in Jalisco by the Late Cretaceous and migrated to the SE until it reached the Isthmus of Tehuantepec by the Middle Miocene. In Oaxaca, the Oligocene-Miocene coastal belt of granitic-granodioritic intrusions accounts for some IOCG deposits, especially in its easternmost portion, which then continues to the Coastal Chiapanecan Neogene batholithic belt. In W-NW Oaxaca, the intracontinental igneous province of the SMS marked the beginning of Cenozoic magmatism and is represented by thick volcanic-hypabyssal successions along with minor intrusions, with which copious magmatic-hydrothermal deposits are associated. Early Eocene and mid-Oligocene volcanism is restricted to the western half of the state, where basic-to intermediate-composition effusive products occur in the Mixteca and western Oaxaca tectonostratigraphic terranes. During this time span, many low-to intermediate-sulfidation epithermal, Fe-rich (IOCG) and polymetallic skarn deposits were produced. However, the ldquo;boom rdquo; in magmatic -hydrothermal mineralizations occurred during the terminal pulses of the SMS volcanism (Miocene), which comprise profuse intermediate volcanic rocks capped by the outburst of silicic magmatism. The early-to mid -Miocene event constitutes the most prominent in terms of metal endowment and diversity of ore deposit types, accounting for about 250 deposits and occurrences in the central and near-eastern portions of the state, which are ascribed to low-to intermediate-sulfidation epithermal, sulfide skarns, IOCG ldquo;clan rdquo; and Cu( ndash;Mo) porphyry types. Among these, epithermal deposits are, by far, the most abundant type. Recent Ti-rich beach deposits and Au alluvial placers are present in southern and easternmost Oaxaca, respectively. In addition, supergene enrichment zones and uneconomic laterites occurrences are found in some localities. Oaxacan ore deposits can be grouped into five major metallogenic epochs: 1) Meso-Neoproterozoic REE-Th-U-Ti deposits and, possibly, orogenic gold lodes during the Olmecan-Zapotecan events (assembly of Rodinia); 2) feasible late Carboniferous-Permian (?) orogenic gold deposits; 3) early Eocene Ag ndash;Au ndash;Pb ndash;Zn ndash;Fe deposits during the onset of the SMS volcanic activity; 4) mid-Oligocene Ag ndash;Pb ndash;Zn
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