After reading this article, you should be able to: Recognise the contribution of medication to male factor infertility; Be aware of drugs that are potentially teratogenic and advise patients to seek advice from their specialist team prior to attempting conception; Understand the rationale and evidence base of medical treatments for male factor infertility; Appreciate the duration and potential side effects of pharmacological treatment of male factor infertility. Infertility is the inability to conceive after one year of regular unprotected intercourse. It is estimated that infertility affects one in seven heterosexual couples in the UK, with 30 of these cases being attributed to the manl. In a quarter of cases, no identifiable cause is found and male factor subfertility is classed as idiopathic2.
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