Purpose: To assess the agreement between two swept-source ocular coherence tomography biometers: ANTERION and IOLMaster 700. Methods: In this prospective comparative study, biometry was consecutively scanned with the IOLMaster 700 and ANTERION. The following were assessed: flat (K1), steep (K2) and mean (Km) keratometry for anterior, posterior and total cornea; lens thickness (LT); anterior chamber depth (ACD); central corneal thickness (CCT); white-to-white (WTW); and axial length (AL). Inter-device mean difference and 95 limits of agreement (LoA) were determined. Differences were considered clinically significant if spherical refractive outcome was altered by ≥0.25D. Results: In 159 eyes of 91 patients, statistically significant differences were found for anterior, posterior and total keratometry. Comparing ANTERION to IOLMaster 700, mean difference (lower ~ upper limits of agreement) were: anterior-K1: -0.17D (-1.07 ~ 0.70), anterior-K2: -0.18D (-1.15 ~ 0.81), anterior-Km: -0.17 (-1.05 ~ 0.69), posterior-K1: -0.38D (-0.57 ~ -0.19), posterior-K2: -0.36D (-0.51 ~ -0.21), posterior-Km: -0.37 (-0.51 ~ -0.23), total-K1: -0.65 (-1.49 ~ 0.18), total-K2: -0.82 (-1.74, ~ 0), total-Km: -0.74 (-1.36 ~ -0.11). Posterior and total-K differences were clinically significant. Differences in LT: 0.159 mm (-0.734 - 1.053), CCT: -0.004 mm (-0.019 ~ 0.011), ACD: 0.054 mm (-0.148 ~ 0.257), WTW: -0.152 mm (-0.783 ~ 0.478) were statistically but not clinically significant. Difference in AL: -0.004 mm (-0.205 ~ 0.196) was not significant. Conclusion: Between ANTERION and IOLMaster 700, posterior and total keratometry showed statistically and clinically significant differences. Anterior keratometry, LT, CCT, ACD and WTW differences were statistically significant but did not reach the level of clinical significance. No significant difference was found for AL. Posterior and total corneal parameters cannot be considered interchangeable between devices.
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