Association between obesity and atopic dermatitis in children: A case‐control study in a high obesity prevalence population

摘要

Abstract Background/Objective Atopic dermatitis (AD) is a chronic inflammatory skin disease. Research suggests an association between obesity and AD, although evidence is lacking from Latin American populations. This study evaluated the association of obesity with AD in children from Chile, a country with high obesity prevalence. Methods A case‐control study was performed in children with active AD (cases) and healthy controls (HCs) from Santiago, Chile. Body mass index was evaluated by z‐score (z‐BMI), with overweight defined as z‐BMI ≥+1 and <+2, and obesity as z‐BMI ≥+2. Abdominal obesity was defined by a waist circumference‐to‐height ratio (WHR) ≥0.5. AD severity was evaluated by Scoring AD (SCORAD) index. Results A total of 174 children with AD and 101 controls were included. AD patients had similar overweight (27 vs. 28) and obesity (21 vs. 26) rates as HCs (p?=?.65). Abdominal obesity rates were also comparable (64 vs. 62, p?=?.81). In sex‐specific analyses, girls with AD had higher abdominal obesity rates than HCs (71 vs. 53, p?