Highly Stretchable and Flexible Electrospinning-Based Biofuel Cell for Implantable Electronic

摘要

With the emerging demand of implantable microelectronics, it essentiallyrequires the fully integrated and reliable power supplies. The study reportsa stretchable and flexible electrospinning-based glucose/O_2 biofuel cell withglucose oxidase bioanode, Pt/C cathode and thermoplastic polyurethanesubstrate, which is capable for adapting to the various stresses and strainscaused by individual movement. The rigid benzene rings and elastic chainsegments of thermoplastic polyurethane ensure its superior tensile property.Furthermore, the stable covalent connections between the activated carbonnanotubes (CNTs-COOH) and glucose oxidase inside 3D thermoplastic polyurethanenetwork are established by amide reaction to ensure the rapid directelectron transfer of bioanode and stable power output of device in flexibleenvironments. The biofuel cell exhibits an open circuit voltage of 0.575 V, andhigh-power density of 57 μW cm~(?2) in 5 mM glucose. Moreover, the powergenerationproperties of implantable biofuel cell keep steady, and its powerdensity exhibits limited fluctuations on the dorsum of rat when bending,stretching, and twisting in 28 days. There is no obvious local inflammationor systemic abnormalities in rats. It satisfies the impressive biocompatiblerequirement, demonstrating the promising potential of electrospinningbasedbiofuel cell as a robust self-sustained power source for implantableelectronics.