Fungitoxicity of hydroxy‐ and methoxy‐substituted phenyl‐ and naphthyl‐benzofurans, phenylbenzobthiophenes and phenylindoles

摘要

AbstractThe antifungal activitiesin vitroof 43 methoxy‐ and hydroxy‐substituted aryl‐benzofurans, phenylbenzobthiophenes and phenylindoles were compared with those of the unsubstituted compounds. Monohydroxy derivatives were usually the most fungitoxic againstAlternaria brassicicola, Botrytis cinerea, Septoria nodorum, Cladosporium cucumerinnum, Fusarium culmorumandUromyces fahaebut the precise effect of substitution upon activity varied with the nature of the parent aryl‐hetocyclic compound, with the position in the molecule, and with the presence of other substituents. Fangitoxicity did not correlate significantly with the partitioning properties of the molecuie as measured by reversed‐phase thin‐layer chr