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LinguaPhylo: A probabilistic model specification language for reproducible phylogenetic analyses

机译:LinguaPhylo:一种用于可重复系统发育分析的概率模型规范语言

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摘要

Phylogenetic models have become increasingly complex, and phylogenetic data sets have expanded in both size and richness. However, current inference tools lack a model specification language that can concisely describe a complete phylogenetic analysis while remaining independent of implementation details. We introduce a new lightweight and concise model specification language, 'LPhy', which is designed to be both human and machine-readable. A graphical user interface accompanies 'LPhy', allowing users to build models, simulate data, and create natural language narratives describing the models. These narratives can serve as the foundation for manuscript method sections. Additionally, we present a command-line interface for converting LPhy-specified models into analysis specification files (in XML format) compatible with the BEAST2 software platform. Collectively, these tools aim to enhance the clarity of descriptions and reporting of probabilistic models in phylogenetic studies, ultimately promoting reproducibility of results.
机译:系统发育模型变得越来越复杂,系统发育数据集在规模和丰富度上都得到了扩展。然而,目前的推理工具缺乏一种模型规范语言,该语言可以简洁地描述完整的系统发育分析,同时保持独立于实现细节。我们引入了一种新的轻量级和简洁的模型规范语言“LPhy”,它被设计为既是人类的,也是机器可读的。“LPhy”附带一个图形用户界面,允许用户构建模型、模拟数据并创建描述模型的自然语言叙述。这些叙述可以作为手稿方法部分的基础。此外,我们还提供了一个命令行界面,用于将 LPhy 指定的模型转换为与 BEAST2 软件平台兼容的分析规范文件(XML 格式)。总的来说,这些工具旨在提高系统发育研究中概率模型的描述和报告的清晰度,最终促进结果的可重复性。

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