Poly(2-oxazoline)s: synthesis and biomedical applications

摘要

With the advancement of medical technology, the previous biomedical material platforms have been unable to meet the increasingly diverse application requirements, and the emergence of poly(2-oxazoline)s provides an opportunity to develop the next generation of biomedical materials. The highly tunable structure and function of poly(2-oxazoline)s, with excellent physical and biological properties, have shown great potential for application in the initial exploratory work. Currently, there are a lot of applied studies related to the water solubility, invisibility, and thermoresponsive of poly(2-oxazoline)s, mainly focused on drug delivery, protein modification, gene carriers, anti-fouling interface, cell sheet engineering, and hydrogel. This paper describes the preparation and physicochemical properties of poly(2-oxazoline)s and reviews the recent applications of poly(2-oxazoline)s in the biomedical field.