Socioeconomic characteristicscomma; life stylecomma; diabetescomma; family history of cancer and risk of pancreatic cancer

摘要

Objective:To investigate the relationship between socioeconomic characteristics, life style (coffee, alcohol and tobacco consumption), diabetes mellitus, first-degree family history of cancer and risk of exocrine pancreatic cancer.Design:Hospital-based case-control study.Methods:One hundred and fifty patients with exocrine panceatic cancer and 160 hospital controls were interviewed by trained personnel when still in hospital.Results:A statistically significant trend of increased risk of exocrine pancreatic cancer with a higher level of education was observed relative risk (RR) = 1.55, confidence interval (Q) 1.10ndash;2.19. No association with other social characteristics (marital status, occupation and place of residence) and coffee, alcohol and tobacco consumption was found. There was a significantly increased risk of exocrine pancreatic cancer as the weekly consumption of spirits increased (RR = 1.52, Cl 1.06ndash;2.19). Diabetes was associated with an increased risk of exocrine pancreatic cancer only when diagnosed less than 1 year prior to the interview (RR = 8.14, Cl 2.19ndash;30.4).Conclusions:Our study confirms that there is an increased risk of exocrine pancreatic cancer associated with alcohol consumption. In addition, we observed a relationship between high socioeconomic status and risk of developing exocrine pancreatic cancer.