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Drug and alcohol positivity of traumatically injured patients related to COVID-19 stay-at-home orders

机译:与 COVID-19 居家令相关的创伤性损伤患者的药物和酒精阳性

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Background: COVID-19 related stay-at-home (SAH) orders created many economic and social stressors, possibly increasing the risk of drug/alcohol abuse in the community and trauma population. Objectives: Describe changes in alcohol/drug use in traumatically injured patients after SAH orders in California and evaluate demographic or injury pattern changes in alcohol or drug-positive patients. Methods: A retrospective analysis of 11 trauma centers in Southern California (1/1/2020-6/30/2020) was performed. Blood alcohol concentration, urine toxicology results, demographics, and injury characteristics were collected. Patients were grouped based on injury date - before SAH (PRE-SAH), immediately after SAH (POST-SAH), and a historical comparison (3/19/2019-6/30/2019) (CONTROL) - and compared in separate analyses. Groups were compared using chi-square tests for categorical variables and Mann-Whitney U tests for continuous variables. Results: 20,448 trauma patients (13,634 male, 6,814 female) were identified across three time-periods. The POST-SAH group had higher rates of any drug (26.2 vs. 21.6 and 24.7, OR = 1.26 and 1.08, p .05).Conclusion: This Southern California multicenter study demonstrated increased amphetamine, MDMA, and THC positivity in trauma patients after SAH, but no difference in alcohol positivity or blood concentration. Drug prevention strategies should continue to be adapted within and outside of hospitals during a pandemic.
机译:背景:与 COVID-19 相关的居家 (SAH) 命令造成了许多经济和社会压力源,可能增加社区和创伤人群吸毒/酗酒的风险。目的:描述加利福尼亚州 SAH 命令后创伤性损伤患者酒精/药物使用的变化,并评估酒精或药物阳性患者的人口统计学或损伤模式变化。方法:对南加州 11 个创伤中心(2020 年 1 月 1 日至 2020 年 6 月 30 日)进行回顾性分析。收集血液酒精浓度、尿液毒理学结果、人口统计学和损伤特征。根据受伤日期(SAH前(SAH前)、SAH后(SAH后)和历史比较(2019年3月19日至2019年6月30日)(对照)对患者进行分组,并在单独的分析中进行比较。使用分类变量的卡方检验和连续变量的 Mann-Whitney U 检验对各组进行比较。结果:在三个时间段内确定了 20,448 名创伤患者(13,634 名男性,6,814 名女性)。POST-SAH组的任何药物(26.2%对21.6%和24.7%,OR=1.26和1.08,p 0.05)。结论:这项南加州多中心研究表明,SAH 后创伤患者的苯丙胺、MDMA 和 THC 阳性率增加,但酒精阳性率或血液浓度没有差异。在大流行期间,应继续在医院内外调整药物预防策略。

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