Phosphatidylinositol 3-kinase Glu545Lys and His1047Tyr Mutations are not Associated with T2D

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机译：磷脂酰肌醇 3-激酶 Glu545Lys 和 His1047Tyr 突变与 T2D 无关

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摘要

Background: Insulin resistance initiated in peripheral tissues induces type 2 diabetes (T2D). It occurs when insulin signaling is impaired.

机译：背景：外周组织中引发的胰岛素抵抗会诱发 2 型糖尿病（T2D）。当胰岛素信号传导受损时，就会发生这种情况。

来源
《Current diabetes reviews》 |2020年第8期|881-888|共8页
作者
Elfaki Imadeldin; Mir Rashid; Abu-Duhier Faisel M.Khan RoaidSakran Mohammed;
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作者单位

Univ Tabuk, Fac Sci, Dept Biochem, Tabuk, Saudi Arabia;

Univ Tabuk, Prince Fahd bin Sultan Res Chair PFBSRC, Fac Appl Med Sci, Med Lab Technol Dept, Tabuk;

King Salman Armed Forces Hosp, Dept Endocrinol, Tabuk, Saudi Arabia;

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收录信息
原文格式 PDF
正文语种英语
中图分类内分泌腺疾病及代谢病;
关键词
Phosphatidylinositol 3-kinase; type 2 diabetes; Glu545Lys (rs104886003); His1047Tyr (rs121913281); single nucleotide polymorphism; insulin resistance; mutations;

机译：磷脂酰肌醇3-激酶;2型糖尿病;Glu545Lys （rs104886003）;His1047Tyr （rs121913281）;单核苷酸多态性;胰岛素抵抗;突变;