The role of electrical property in determining the response of 20H-80S composite thin films fabricated for biological applications

摘要

The exploration of exquisite electrical properties of biomaterials for clinical applications is driven by natural design. Inspired by the idea, composite thin films of varying thickness fabricated from a sputtering target of composition 20 at.% Ca-10(PO4)(6)(OH)(2) (HAP) and 80 at.% SrTiO3 (ST) over Ti (and n-type Si) are reported. The preliminary studies establish that thicker composite films have improved microstructural properties. The films are found to be cytocompatible showing improved cell viability >100 % for all the films, desirable for inducing metabolic reactions in-vivo. The electrical properties of the thin films are probed by considering the frequency and temperature variation of the dielectric properties. The dielectric properties of the thin films are essential and may augment the biological responses of implants by enabling expedited healing, subject to further clinical trials. The mechanism may related to the polarization of the dipoles, elaborated in the article. Also, associated are the loss mechanisms that continuously disrupt the polarization, hindering the faster healing process of bone fractures. A comprehensive analysis of such loss mechanisms is presented. The article closes with the electrical blueprint of the thin films in the form of a parallel QR circuit obtained by Cole-Cole analysis. The understanding of the electrical properties provides fresh insights on the behavior of the thin films for designing electro-active implants. [GRAPHICS] .