The Effect and Safety of Aerobic Interval Training According to Exercise Intensity in Acute Coronary Syndrome

摘要

Supplemental Digital Content is Available in the Text. Maximal-intensity aerobic interval training (95%-100% of the heart rate reserve) was superior to high-intensity aerobic interval training at improving exercise capacity in patients with acute coronary syndrome. No major cardiovascular or other musculoskeletal complications occurred during the maximal- or high-intensity aerobic interval training. Purpose: To evaluate the effect of increasing the maximal oxygen uptake ( o _(2max)) and the safety of maximal-intensity aerobic interval training (MAIT) compared with high-intensity aerobic interval training (HAIT). Methods: Forty-seven patients with first-ever acute coronary syndrome were assigned to MAIT or HAIT. Subjects underwent adaptation period during the first 2 wk of cardiac rehabilitation and then MAIT at 95-100% of the heart rate reserve or HAIT at 85% of the heart rate reserve, 3 d/wk for 4 wk. The primary outcome was o _(2max). The secondary outcomes were major cardiovascular complications, hemodynamic responses, myocardial oxygen demand, cardiometabolic health, and echocardiographic findings. Results: A total of 670.5 hr of MAIT and HAIT were completed. After 6 wk of aerobic interval training, o _(2max)was significantly increased in both groups. However, the increment of o _(2max)was significantly greater in the MAIT group than in the HAIT group ( P < .05). The percentage increases for MAIT and HAIT were 31% and 17%, respectively. No major cardiovascular or musculoskeletal complications were noted. Conclusions: The results of this study indicate that 6 wk of MAIT resulted in statistically significantly better improvement in o _(2max)than 6 wk of HAIT at a similar total work in patients with acute coronary syndrome. Moreover, both MAIT and HAIT may be safe to use in the cardiac rehabilitation setting.