Single-Dose Oral NSAIDs and Acetaminophen for Perineal Pain in the Early Postpartum Period

摘要

Is a single dose of an oral nonsteroidal anti-inflammatory drug (NSAID) or acetaminophen effective for acute perineal pain in the early postpartum period?In patients with acute perineal pain at four hours' postpartum, a single dose of an oral NSAID (number needed to treat NNT = 4; 95 CI, 3 to 6)1 and a single dose of oral acetaminophen (NNT = 3; 95 CI, 2 to 6)2 are each effective at achieving adequate pain relief. Both NSAIDs (NNT = 5; 95 CI, 4 to 8) and acetaminophen (NNT = 5; 95 CI, 4 to 7) are effective at reducing the need for further analgesia. It is unclear whether an NSAID or acetaminophen is superior. It should be noted that these data are based on studies in which a majority of patients underwent episiotomy.1'2 (Strength of Recommendation: B, based on inconsistent or limited-quality patient-oriented evidence.)