The risks posed to unborn babies if women take valproate during pregnancy have been known, in some capacity, for more than 40 years. The latest estimates (https://www.gov.uk/guidance/valproate-use-by-women-and-girls) are that up to four in ten babies are at risk of developmental disorders if valproate is taken during pregnancy, and approximately one in ten exposed babies are at risk of birth defects, such as spina bifida or malformations of the face, skull and limbs.
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