Direct oral anticoagulants in the treatment of portal vein thrombosis: a therapeutic review

摘要

The current recommended treatment for portal vein thrombosis (PVT) is low molecular weight heparins (LMWH) or oral vitamin K antagonists, such as warfarin, for at least three or six months. There has been growing interest among clinicians within our tertiary referral centre for liver disease at King’s College Hospital (KCH) to prescribe direct oral anticoagulants (DOACs) for PVT. There is a lack of trial data and guidelines available for this indication; therefore, a comprehensive therapeutic review was conducted to inform best evidence-based practice. ?