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Recent Progress in the Biological Applications of Reactive Oxygen Species-Responsive Polymers

机译:活性氧响应聚合物的生物学应用研究进展

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摘要

Responsive polymeric materials that are sensitive to biological stimuli including temperature, pH, enzymes, or redox conditions have attracted research interest in recent years. Among these, reactive oxygen species (ROS)-responsive polymers are particularly appealing because of the special role of ROS in living organisms. ROS are the indicator and cause of certain diseases, and they are also important signaling molecules. ROS-responsive polymers could possess the following functions: drug carriers, ROS probes, or medications for certain ROS-related diseases. In this review, we analyze the progress about ROS-responsive polymers made in recent years and predict the future trends of ROS-responsive polymers from the above mentioned perspectives. Due to the limited scope of this review, some older articles are not covered here and are left for more comprehensive reviews.
机译:近年来,对温度、pH值、酶或氧化还原条件等生物刺激敏感的响应性聚合物材料引起了研究兴趣。其中,活性氧(ROS)响应聚合物特别有吸引力,因为ROS在生物体中具有特殊作用。ROS是某些疾病的指标和病因,也是重要的信号分子。ROS响应性聚合物可能具有以下功能:药物载体、ROS探针或某些ROS相关疾病的药物。本文分析了近年来ROS响应聚合物的研究进展,并从上述角度预测了ROS响应聚合物的未来趋势。由于本综述的范围有限,一些较早的文章在此不予涵盖,留待更全面的综述。

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