Ultrasound- and Microwave-promoted Synthesis, Growth-regulating Activity and Antimicrobial Behavior of Trimecaine-based Ionic Compounds

摘要

The present work describes the synthesis, growth-regulating activity, and antimicrobial behavior of ionic compounds based on 2-diethylamino-N-(2,4,6-trimethylphenyl)acetamide (trimecaine). Synthesis of ionic compounds was performed via N-alkylation of trimecaine with alkyl halides using microwave and ultrasound activation and the results were compared with those of classical conditions (thermal activation). The synthesized ionic compounds have been tested for germination energy and capacity with the collection of different varieties and hybrids of sweet sorghum seeds. The valuable results were obtained for the seeds stored for several years for which the significant drop in germination activity is usually observed. Furthermore, the ionic compounds were used to study their biological activity - growth -regulating activity on sweet sorghum seeds and the antimicrobial behavior against E. coli, S. typhimurium, B. subtilis, S. aureus, P. aeruginosa, and C. albicans microorganisms.