Therapeutic drug monitoring (TDM) is a test that measures the amount of a particular drug in the blood. It is done to make sure that the amount of medicine you are taking is safe and effective. Most medicines can be given correctly without any special tests. However, with certain types of drugs, it can be difficult to find a dose that contains enough drugs to treat the condition without causing dangerous side effects. TDM helps your doctor make sure you are taking the right amount of medication. Therapeutic drug monitoring (TDM) is also known as clinical practice in which specific drugs are measured at specific intervals in order to keep the concentration in the patient's bloodstream constant and thereby optimize individual dosing regimens. It has been found that most drugs do not require the use of TDM, mainly drugs with a narrow range of treatment, drugs with significant pharmacokinetic fluctuations, drugs whose target concentration is difficult to monitor, and drugs that have therapeutic effects and cause adverse effects. It is used to monitor the drugs that are being used. The process of TDM is based on the assumption that there is a clear relationship between dose and plasma or blood drug concentration, and between concentration and therapeutic effect. TDM begins with the initial prescribing of the drug and involves determining an initial dosing regimen that suits the patient's characteristics such as clinical condition and age, weight, organ function, and concomitant drug therapy. Factors such as sampling time, dosing history, patient response, and desirable medical goals related to drug dosage should be considered when interpreting concentration measurements. The goal of TDM is to use appropriate concentrations of difficult to manage medications to optimize clinical outcomes in patients in various clinical situations.
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