Determination of Solvation Effects in Liquid Adsorption Chromatography with Mixed Mobile Phases

摘要

A model of chromatographic process, involving formation of multimolecular solute-solvent solvates in the mobile phase, is discussed. This model leads to an equation describing dependence of the capacity ratio upon mobile phase composition. The TLC data for some solutes chromatographed in n-heptane+chloroform on silica gel are interpreted by means of the above equation.