Cleaning and disinfection of surfaces are not only the essential steps for maintaining the cleanliness and control of the manufacturing environment, but it is also one of the most important pillars of the Contamination Control framework. The overall regulatory expectations regarding this topic are well described: a. Any building used in the manufacture, processing, packing, or holding of a drug product shall be maintained in a clean and sanitary condition, any such building shall be free of infestation by rodents, birds, insects, and other vermin (other than laboratory animals). Trash and organic waste matter shall be held and disposed of in a timely and sanitary manner. b. There shall be written procedures assigning responsibility for sanitation and describing in sufficient detail the cleaning schedules, methods, equipment, and materials to be used in cleaning the buildings and facilities; such written procedures shall be followed.
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