Novel first-generation dendrimers on calix4resorcinol core equipped with multiple triazole units

摘要

Novel first-generation dendrimers on the calix4resorcinol core with four branches each containing multiple 1,2,3-triazole units have been synthesized in one-step by acid catalyzed condensation of resorcinols with a new aldehyde dendron, namely, 4-{3,5-bis(1-benzyl-1H-1,2,3-triazol-4-yl)-methoxybenzyloxy}benzaldehyde (obtained by alkyne- azide cycloaddition). The reaction proceeds stereoselectively to form rccc-diastereoisomers in high yields.