Multicomponent Reaction of Pyridinium Salts, beta-Nitrostyrenes and Ammonium Acetate under the DBU/Acetic Acid System: Access to 2,4,6-Triarylpyridine Derivatives

摘要

abstract_textpA four-component reaction of pyridinium salts, substituted beta-nitrostyrenes and ammonium acetate as a nitrogen source using acetic acid as solvent was investigated to develop an efficient divergent route for the synthesis of 2,4,6-trisubstituted pyridines. This efficient method provides fast access to a variety of structurally diverse pyridine derivatives. The structure of a typical product was confirmed by X-ray crystallography./p/abstract_text