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Carrying on with liver transplantation during the COVID-19 emergency: Report from piedmont region

机译:在 COVID-19 紧急情况下继续进行肝移植:来自皮埃蒙特地区的报告

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摘要

Background: The COVID-19 pandemic is an emergency worldwide. In Italy, liver transplant activity was carried on, but despite all efforts, a 25 reduction of procured organs has already been observed during the first 4 weeks of the outbreak. Aims: To analyze if our strategy and organization of LT pathway during the first two months of the COVID-19 emergency succeeded in keeping a high level of LT activity, comparing the number of LT in the first two months with the same period of time in 2019. Methods: We compared the liver transplants performed in our Center between February 24th and April 17th, 2020 with liver transplants performed in the same period in 2019. Results: In 2020, 21 patients underwent liver transplantation from deceased donors, exactly as the year before, without statistically significant difference. All patients survived in both groups, and the rate of early graft dysfunction was 24 in 2020 and 33 in 2019. In 2020 Median MELD was higher (17 vs 13). We were able to perform 3 multiorgan transplants and one acute liver failure. Nobody died on waiting list. The performance of our Center, despite the maxi-emergency situation, was steady and this was the result of a tremendous team working within the hospital and in our region. Conclusions: Team working allowed our Center to maintain its activity level, taking care of patients before and after liver transplantation. Sharing our experience, we hope to be helpful to other Centers that are facing the pandemic and, if another pandemic comes, to be more prepared to deal with it.
机译:背景:COVID-19 大流行是全球范围内的紧急情况。在意大利,肝移植活动仍在继续,但尽管做出了所有努力,但在疫情爆发的前 4 周内,已经观察到采购器官减少了 25%。目的:分析我们在 COVID-19 紧急情况的前两个月的 LT 途径策略和组织是否成功地保持了高水平的 LT 活动,将前两个月的 LT 数量与 2019 年同期进行比较。方法:比较2020年2月24日至4月17日在本中心实施的肝移植手术与2019年同期实施的肝移植手术。结果:2020 年,21 例患者接受了已故供体肝移植,与前一年完全相同,差异无统计学意义。两组患者均存活,2020年早期移植物功能障碍发生率为24%,2019年为33%。2020 年,MELD 中位数更高(17 对 13)。我们能够进行 3 例多器官移植和 1 例急性肝衰竭。没有人死在等候名单上。尽管处于最紧急的状况,但我们中心的表现仍然稳定,这是医院和我们地区庞大团队工作的结果。结论:团队合作使本中心保持了活动水平,照顾了肝移植前后的患者。通过分享我们的经验,我们希望对其他面临大流行的中心有所帮助,如果另一场大流行来临,我们能做好应对的准备。

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