Cognitive impairment is emerging as an important therapeutic target in patients with major depressive disorder. Measuring cognitive changes subjectively and objectively in major depressive disorder is challenging. However, subjective cognitive assessments may have greater relevance to real-world situations because neuropsychological assessment has many limitations for routine clinical use. The objective of this article is to briefly review and summarize THINC-it, the Perceived Deficits Questionnaire, the British Columbia Cognitive Complaints Inventory, and the Cognitive and Physical Functioning Questionnaire, which are representative samples of subjective cognitive assessment tools currently available to assess cognitive function in patients with depression. [Psychiatr Ann. 2022;52(3):105-108.]
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