Association between Single Nucleotide Polymorphisms in TYW5 Locus and Beef Amino Acids Content in Shuxuan Cattle

摘要

Background: Shuxuan cattle is a crossed cattle breed in southwest of China, by crossing the indigenous Bashan cattle with two exotic breeds. The objective of this study was to estimate allele frequencies of the g.88925365A>C in TYW5 gene in Shuxuan cattle and to evaluate association between this polymorphism and meat quality traits. Methods: The SNP g.88925365A>C was genotyped in 151 Shuxuan cattle and subjected to association analysis with the 17 amino acid content and total amino acid. Result: The AC was the main genotype with 41.06% and C was the predominant allele with 50.99% at this locus. The allele diversity based on the He (0.4998), Ne (1.9992) and PIC (0.3749) revealed moderate genetic variation within Shuxuan cattle population. Significant association (P<0.05) was observed between the polymorphism and six amino acid content (Glu, Asp, Val, Ile, Ser and Cys). These results provided a potential genetic marker for the genetic improvement of meat quality in Shuxuan cattle.