Abstract Purpose The purpose of this study was to investigate the impact of various methods on the assessment of vertebral bone quality.Methods A consecutive series of 427 candidates for lumbar disc replacement with lumbar DEXA and MRI and/or CT scans were included. Two measurement techniques were used on CTs—a sagittal and axial. From axial images, the upper, mid, and lower portions of each vertebral body were measured. Four MRI vertebral bone quality (VBQ) calculations were generated using separate equations.Results All CT measures were highly correlated with each other, regardless of measurement or calculation method (range 0.925–0.995). Sagittal measurements were highly correlated with axial (r?=?0.928, p?
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