机译:逃离平原:多参数优化导致发现新型四氢吡啶并4,3-d嘧啶衍生物作为人类免疫缺陷病毒-1非核苷类逆转录酶抑制剂抑制剂,对非核苷类逆转录酶抑制剂耐药变体具有优异的抗病毒活性和有利的药物样特征
Shandong Univ;
Katholieke Univ Leuven;
China Belgium Collaborat Res Ctr Innovat Antiviral;
MEDICINAL CHEMISTRY; RILPIVIRINE; STRATEGIES; MUTATION; E138K; PREDICTIONS; SOLUBILITY; Y181C;