Estimation and comparison of salivary flow rate and its composition in diabetic patients and nondiabetic patients: A pilot study

摘要

Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemiairregularities in the metabolism of carbohydrates, lipids and protein. It is often associated with thedevelopment of microvascular and macrovascular complications and neuropathies. The health of oraltissues is known to be related to the quality and quantity of saliva both of which may be altered in diabetes.Aim: The aim of the present study was to determine the salivary flow rate, electrolytes and total proteinsin saliva of Type II diabetic patients.Materials and Methods: A total number of 120 participants were included in this study, in which 80 patientswere suffering from Type II DM (which included both controlled and uncontrolled diabetes) and 40nondiabetic persons (controls). The study population included both the genders, with an age range of40–70 years. The study population was divided into three groups.Results: The values of total protein, sodium, potassium and salivary flow rate among controls, controlleddiabetes and uncontrolled diabetes were collected, formulated and multiple comparisons between thegroups using the analysis of variance and post hoc Tukey honestly significant difference analysis were donein version 16.0 of SPSS software.Conclusion: Studies with larger sample size are warranted to know the exact pathophysiology of controlledand uncontrolled Type II DM in terms of salivary flow rate, salivary electrolytes and total protein.