Clinical profile and treatment outcomes of patients with ectopic ACTH syndrome compared to Cushing disease: a single-center experience

摘要

Abstract Purpose We aimed to evaluate and compare the clinical, biochemical and radiological profile and outcomes of patients with ectopic ACTH syndrome (EAS) and Cushing disease (CD) treated over a period of 10 years (2013–2022).Methods In this ambispective observational study, we collected data for 146 patients with ACTH-dependent CS (EAS, n?=?23; CD, n?=?94; occult ACTH source, n?=?29). Relevant details were filled in a predesigned proforma and outcomes were ascertained at the most recent visit.Results EAS was more common in males (65.2 vs. 27.6%, p?