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The Association Between Hospital Length of Stay and Treatment With IV Magnesium in Patients With Status Migrainosus

机译:偏头痛持续状态患者住院时间与静脉注射镁治疗之间的关联

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摘要

Status migrainosus (SM) is a subtype of migraine defined by migraine lasting >72 hours and is difficult to treat in clinical practice. Magnesium is commonly used in the treatment of migraine. We conducted a retrospective cohort study to determine if length of admission was associated with IV magnesium therapy in patients with SM. We reviewed the charts of all patients admitted to a large military treatment facility from October 2013 to December 2018 with the admission diagnosis of migraine. There were 333 patients that were reviewed and 141 met the inclusion criteria. Nearly half of patients received IV magnesium therapy with routine care (46.8, n = 66). IV magnesium therapy was not associated with length of admission (58 hours (IQR 25.5, 86) compared to 42 hours (IQR 25.5, 80.5) respectively, p = 0.47). Of the cases without Neurology consultation, patients who received magnesium therapy (n = 5) had numerically shorter admission but this difference did not meet statistical significance (n = 12) (17 hours (IQR 13.75, 31.25) versus 24.5 hours (IQR 15.25, 58.75), p = 0.0534). This study contributes to the limited pool of available data on the treatment of SM. Prospective research is needed to study magnesium therapy in patients with prolonged migraine.
机译:偏头痛持续状态 (SM) 是偏头痛的一种亚型,其定义为偏头痛持续 >72 小时,在临床实践中难以治疗。镁通常用于治疗偏头痛。我们进行了一项回顾性队列研究,以确定SM患者的入院时间是否与静脉注射镁治疗相关。我们回顾了 2013 年 10 月至 2018 年 12 月期间入住大型军事治疗机构并诊断为偏头痛的所有患者的图表。共有 333 名患者接受了审查,其中 141 名符合纳入标准。近一半的患者接受了静脉镁治疗和常规护理(46.8%,n = 66)。静脉注射镁治疗与入院时间无关(58 小时 (IQR 25.5, 86) 与 42 小时 (IQR 25.5, 80.5) 相比,p = 0.47)。在未进行神经内科会诊的病例中,接受镁治疗的患者(n = 5)的入院时间较短,但这种差异不符合统计学意义(n = 12)(17小时(IQR 13.75,31.25)与24.5小时(IQR 15.25,58.75),p = 0.0534)。本研究有助于 SM 治疗的可用数据有限。 需要前瞻性研究来研究镁治疗长期偏头痛患者。

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