Engineering a Culturable Serratia symbiotica Strain for Aphid Paratransgenesis Aphids are global agricultural pests and important model organisms for studying bacterial symbiosis, but none of their native symbionts have been genetically manipulated to date. Elston et al. (e02245-20) characterized genetic tools and techniques that can be used to engineer a gut-associated symbiont, Serratia symbiotica CWBI-2.3T. A green fluorescent protein-tagged strain was used to study how rapidly this bacterium colonizes several aphid species and its effects on host fitness. This work serves as a foundation for understanding the evolution of this symbiont species and the development of symbiont-based techniques for studying and controlling aphids.
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