Ni_3V_2O_8 Nanosheets Grafted on 3D Helical-shaped Carbon Nanocoils as A Binder-free Hierarchical Composite for Efficient Non-enzymatic Glucose Sensing

摘要

High fabrication cost, chemical instability, and complex immobilization ofenzyme molecules are critical issues of enzyme-based glucose sensors.Designing state-of-the-art, binder-free, and non-enzymatic glucose sensingprobes plays an imperative role to cope with the aforementioned issues. 3D carbonaceousnanomaterials coated with transition metal vanadates (TMVs) are afavorable biomimetic platform for glucose quantification. Peculiar hierarchicalstructure, enhanced conductivity, synergistic interaction, multiple oxidationstates, and high catalytic activity would make such composite a potential contenderfor non-enzymatic glucose sensing. Herein, 3D helical-shaped carbonnanocoils (CNCs) are grown on nickel foam (NF) via chemical vapor depositionmethod to prepare a robust CNCs/NF scaffold. Then, a hydrothermal route isfollowed to grow interconnected free-standing Ni_3V_2O_8 nanosheets (NSs) onCNCs/NF scaffold. This novel and binder-free Ni_3V_2O_8 NSs/CNCs/NF hierarchicalcomposite possesses superior electrochemical active area (ECSA) andexceptional electrochemical efficacy. Amperometric analysis exhibits extremelyprompt detection time (0.1 s), elevated sensitivity (5214 μA mM~(?1) cm~(?2)), andlow detection limit (0.04 μM). Developed sensor demonstrates appreciablerecoveries (93.3 to 103.3%) regarding glucose concentration in human serum.The appealing analytical results show that deployment of a 3D helical-shapedhierarchical smart scaffold can be an effective strategy for developing efficientand advanced non-enzymatic glucose sensors.