One of the most common pharmaceutical dosage forms in drug delivery is the tablet; they're a favorable dosage form for several reasons: dosing accuracy, physical and chemical stability, competitive production costs, high level of patient compliance and more. Traditionally, manufacturers have relied on the well-established wet granulation process for tableting. While it's effective, wet granulation is a time-consuming technique that can be costly and can lead to product cross-contamination or material loss during manufacturing. Many manufacturers seeking to save time and money, improve efficiency and respond quickly to market changes, have already made the transition from wet granulation to direct compression (DC). The resource saving technique has evolved in the past few decades to inspire wide adoption throughout the pharmaceutical community. As the most straightforward manufacturing option with the fewest manufacturing steps, DC is the easiest to control manufacturing process for tablets, as well as the most cost-effective.
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