The use of autologous dentin as an alternative to conventional regeneration biomaterials has become increasingly common, having been described in the literature since the 1960s, demonstrating its efficacy. Certain components that form the teeth, such as type 2 bone morphogenetic proteins (BMP-2), type I collagen, and hydroxyapatite, have been widely proven to be effective and are essential materials in the regeneration of alveolar bone. It is known that regenerated bone is histologically indistinguishable from native bone, and therefore, conditions and materials that allow for adequate replacement by host bone and that do not persist over time are key. With the present case report, encouraging advances in the use of autologous dentin as a graft material are demonstrated. Int J Periodontics Restorative Dent 2021;41:835-842. doi: 10.11607/prd.5183
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