Insulinomas are functional insulin-secreting tumours of the beta cells of the pancreatic islets which are rare in cats. Clinical signs are a result of hypoglycaemia and include seizures, collapse, weakness, ataxia, disorientation, mental dullness and visual disturbances. An 11-year-old male neutered domestic shorthair cat was presented with a history of having a single abnormal neurological episode. Persistent hypoglycaemia, hyperinsulinaemia and the presence of a well-defined pancreatic nodule on abdominal ultrasound resulted in a suspected diagnosis of insulinoma. Multiphasic CT angiography revealed a well-defined, homogeneous pancreatic mass which was isoattenuating to pancreatic parenchyma on precontrast images, had marked contrast enhancement in the arterial phase and moderate enhancement in the venous phase. CT angiography was a useful imaging modality for evaluating this case of histologically confirmed malignant insulinoma and its associated metastases.
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