机译:Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: A randomized, double-blind, placebo-controlled phase 3 trial
Univ Calif San Diego, San Diego, CA 92103 USA;
Allergy & Asthma Specialists Dallas, Dallas, TX USA;
Asthma & Allergy Specialists, Charlotte, NC USAGoethe Univ Frankfurt, Univ Hosp Frankfurt, Frankfurt, GermanyHarvard Med Sch, Massachusetts Gen Hosp, Boston, MA 02115 USAUniv Cincinnati, Cincinnati, OH USAAllergy & Asthma Clin Res, Walnut Creek, CA USALittle Rock Allergy & Asthma Clin Res Ctr, Little Rock, AR USAUniv Washington Sch Med, Marycliff Clin Res, Spokane, WA USAClin Specialisee Allergie Capitale, Quebec City, PQ, CanadaWashington Univ Sch Med, St Louis, MO USAMed Univ Vienna, Dept Dermatol, Vienna, AustriaMasaryk Univ, Dept Clin Immunol & Allergol, St Annes Univ Hosp Brno, Brno, Czech RepublicFac Hosp, Dept Allergol & Immunol, Plzen, Czech RepublicClin Res Ctr Alabama, Birmingham, AL USAOptimed Res Ltd, Columbus, OH USAPortland Clin Res, Portland, OR USAUniv Ottawa, Ottawa Allergy Res Corp, Dept Med, Ottawa, ON, CanadaUniv Calif Los Angeles, Dept Pediat, Los Angeles, CA 90024 USAIcahn Sch Med Mt Sinai, Dept Med, Div Clin Immunol & Allergy, New York, NY 10029 USAPenn State Univ, Dept Med & Pediat, Hershey, PA USAInst Asthma & Allergy, Chevy Chase, MD USASemmelweis Univ, Dept Internal Med 3, Hungarian Angioedema Reference Ctr, Budapest, HungaryBioCryst Pharmaceut, Durham, NC USACharit Univ Med Berlin, Dept Dermatol & Allergy, Dermatol Allergol, Berlin, Germany;
BCX7353; berotralstat; C1 inhibitor; efficacy; HAE; hereditary angioedema; kallikrein inhibitor; long-term prophylaxis; prophylaxis; safety;