Cation Exchange Liquid Chromatography with Amperometric Detection as a Method for the Analysis of Endogenous Catecholamine Concentrations in Plasma or Serum

摘要

A chromatographic system which permits determination of catecholamines, isolated from a few ml of plasma or serum, is described in detail. Some factors of importance for the improvement of the signal-to-noise ratio at subpicomole detection levels have been carefully investigated.