H‐2 gene complementation in cytotoxic T cell responses of female against male cells

摘要

AbstractH‐2 gene‐dependent nonresponsiveness and responsiveness to H‐2‐matched male cells can be observed in cytotoxic assays in several mouse strains. H‐2 genes of several low responder strains can complement each other in cis or trans position to produce high responders. One of the H‐2 gene products functions at the level of antigen‐presenting cells (stimulators, targets), the other must be expressed in the responding T ce