Specificity of antigen recognition by normal thymus cells in nude mice

摘要

AbstractIf injected with normal thymus cells from BALB/c or BALB/c‐Igb, nude mice from a stock which is partially backcrossed to BALB/c make antibodies to many antigens to which untreated nude mice do not respond. Anti‐Igbcan be made if the thymus donor is BALB/c, but not if the thymus donor is BALB/c‐Igb. If cells from both donor strains are injected, a response is obtained which shows that the unresponsiveness of recipients of BALB/c‐Igb cells is not due to tolerance of donor a